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Wednesday, September 13, 2006

Chemotherapy for hepatobiliary and pancreatic cancer: an overview

Pancreas
CONKO-001, obs
rt+Gem>Fu only in pancreas head cancer
ASCO2006

EORTC 40, 013-22012, Gem vs RT

Biliary
Survival benefit of radiation therapy in advanced case
Hepatogastroenterology. 1999 May-Jun;46(27):1578-84.
Am J Surg. 1990 Jan;159(1):91-7;

CRT and FU synergy
GB R1-2 good

Systemic
Gem in pk RCT
J Clin Oncol. 1997 Jun;15(6):2403-13.
GEM+CDDP better
ASCO2006
Gem alon in CCC
Cancer Chemother Pharmacol. 2006 May;57(5):647-53.

Sorafenib in HCC
Journal of Clinical Oncology, Vol 24, No 26 (September 10), 2006: pp. 4293-4300
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